Doktor Edvin P. Alyea

Doktor Edvin P. Alyea ildiz hujayralari yoki suyak iligi transplantatsiyasini ko'rib chiqayotgan qon saratoni bilan kasallangan bemorlarni davolashga ixtisoslashgan. So'nggi 20 yil ichida transplantatsiya sohasida sezilarli yutuqlarga erishildi, bu esa yaxshi natijalarga olib keldi. Ushbu yutuqlar bemorlarda toksiklikni kamaytirish uchun pastroq kimyoterapiya dozalarini qo'llash qobiliyatini, shuningdek, relaps ehtimolini kamaytirish usullarini o'z ichiga oladi. Men qon saratoni uchun ildiz hujayralari transplantatsiyasidan keyingi natijalarni yaxshilash uchun yangi dori-darmonlar va usullardan foydalanishga qiziqaman. Bemorlarni davolash maqsadlari va eng yaxshi harakat yo'nalishini aniqlash uchun ular bilan hamkorlik qilish juda muhimdir. Transplantatsiya qilinganidan keyin ko'p yillar davomida men bemorlar va ularning oilalari bilan ishlashni yaxshi ko'raman.

Kengashni sertifikatlash

Amerika ichki kasalliklar kengashi, tibbiy onkologiya

Do'stlik

Tibbiy onkologiya, Dana-Farber saraton instituti (Massachusets), 1992-1995

Turar joy

Ichki kasalliklar, Brigham va ayollar kasalxonasi (Massachusets), 1989-1992

ta'lim

MD, Dyuk universiteti, 1989 yil

• Katta yoshli suyak iligi va ildiz hujayra transplantatsiyasi
• Otolog transplantatsiyasi
• Allogeneik transplantatsiya
• Singenik transplantatsiya

• Hourigan, Christopher S., Laura W. Dillon, Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, et al. “Impact of Conditioning Intensity of Allogeneic Transplantation for O'tkir mieloidli leykemiya With Genomic Evidence of Residual Disease.” J Clin Oncol 38, yo'q. 12 (20 yil 2020 aprel): 1273–83. https://doi.org/10.1200/JCO.19.03011.
• Soiffer, Robert J., Haesook T. Kim, Joseph McGuirk, Mitchell E. Horwitz, Laura Johnston, Mrinal M. Patnaik, Witold Rybka, et al. “Prospective, Randomized, Double-Blind, Phase III Clinical Trial of Anti-T-Lymphocyte Globulin to Assess Impact on Chronic Graft-Versus-Host Disease-Free Survival in Patients Undergoing HLA-Matched Unrelated Myeloablative Hematopoietic Cell Transplantation.” J Clin Oncol 35, yo'q. 36 (20 yil 2017 dekabr): 4003-11. https://doi.org/10.1200/JCO.2017.75.8177.
• Liu, Hien Duong, Kwang Woo Ahn, Zhen-Huan Hu, Mehdi Hamadani, Taiga Nishihori, Baldeep Wirk, Amer Beitinjaneh, et al. “Allogeneic Hematopoietic Cell Transplantation for Adult Chronic Myelomonocytic Leukemia.” Biol qon marrow transplantatsiyasi 23, yo'q. 5 (2017 yil may): 767–75. https://doi.org/10.1016/j.bbmt.2017.01.078.
• Scott, Bart L., Marcelo C. Pasquini, Brent R. Logan, Juan Wu, Steven M. Devine, David L. Porter, Richard T. Maziarz, et al. “Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes.” J Clin Oncol 35, yo'q. 11 (10 yil 2017 aprel): 1154–61. https://doi.org/10.1200/JCO.2016.70.7091.
• Shaffer, Brian C., Kwang Woo Ahn, Zhen-Huan Hu, Taiga Nishihori, Adriana K. Malone, David Valcárcel, Michael R. Grunwald, et al. “Scoring System Prognostic of Outcome in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome.” J Clin Oncol 34, yo'q. 16 (1 yil 2016 iyun): 1864–71. https://doi.org/10.1200/JCO.2015.65.0515.
• Devine, Steven M., Kouros Owzar, William Blum, Flora Mulkey, Richard M. Stone, Jack W. Hsu, Richard E. Champlin, et al. “Phase II Study of Allogeneic Transplantation for Older Patients With Acute Myeloid Leukemia in First Complete Remission Using a Reduced-Intensity Conditioning Regimen: Results From Cancer and Leukemia Group B 100103 (Alliance for Clinical Trials in Oncology)/Blood and Marrow Transplant Clinical Trial Network 0502.” J Clin Oncol 33, yo'q. 35 (10 yil 2015 dekabr): 4167-75. https://doi.org/10.1200/JCO.2015.62.7273.
• Jacobson, Caron A., Lixian Sun, Haesook T. Kim, Sean M. McDonough, Carol G. Reynolds, Michael Schowalter, John Koreth, et al. “Post-transplantation B cell activating factor and B cell recovery before onset of chronic graft-versus-host disease.” Biol qon marrow transplantatsiyasi 20, yo'q. 5 (2014 yil may): 668–75. https://doi.org/10.1016/j.bbmt.2014.01.021.
• Cutler, Corey, Haesook T. Kim, Bhavjot Bindra, Stefanie Sarantopoulos, Vincent T. Ho, Yi-Bin Chen, Jacalyn Rosenblatt, et al. “Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial.” qon 122, yo'q. 8 (22 yil 2013 avgust): 1510–17. https://doi.org/10.1182/blood-2013-04-495895.
• Porcheray, Fabrice, David B. Miklos, Blair H. Floyd, Stefanie Sarantopoulos, Roberto Bellucci, Robert J. Soiffer, Joseph H. Antin, Edwin P. Alyea, Jerome Ritz, and Emmanuel Zorn. “Combined CD4 T-cell and antibody response to human minor histocompatibility antigen DBY after allogeneic stem-cell transplantation.” transplantatsiyasi 92, yo'q. 3 (15 yil 2011 avgust): 359–65. https://doi.org/10.1097/TP.0b013e3182244cc3.