Primer karaciğer kanseri asit, sarılık, uzak metastaz vb. ile ilişkili olduğunda buna ileri primer karaciğer kanseri denir. İlerlemiş primer karaciğer kanserinin tedavisi zordur ve klinik tedavi etkisi ideal değildir. Lenf düğümlerine veya diğer organlara yayılmış olması nedeniyle ilerlemiş karaciğer kanserinin tedavisinde cerrahi bir seçenek değildir.
If the liver is in good condition (Child-Pugh grade A or B), the doctor will consider treatment with the targeted therapeutic drugs Sorafenib (Nexavar) or Lenvama (Lenvima). Growth can prolong the survival time of patients. If the patient develops drug resistance, the targeted drug repaglinide (Stivarga) or the immünoterapi drug nivolumab (Opdivo) can be used instead.
In addition, keeping an eye on clinical trial information at any time and actively participating in relevant clinical trials such as chemotherapy, radiotherapy, and immunotherapy may also bring opportunities and hope for patients with advanced karaciğer kanseri. It is hoped that in the next few years, researchers will make a huge breakthrough in the field of liver cancer diagnosis and treatment.