Lagu Mingyang ti Harvard Medical School sareng Rumah Sakit Umum Massachusetts dilaporkeun yén sanggeus diagnosis kanker colorectal non-métastatik, ingesting langkung serat bakal ngurangan mortality husus sarta mortality sakabéh kanker colorectal. Ngaronjatna asupan serat saatos diagnosis tiasa nguntungkeun penderita kanker koloréktal. (JAMA Oncol. Versi online tanggal 2 November 2017).
Although it has been shown that high dietary fiber intake reduces the risk of colorectal cancer, it is not clear whether high fiber intake will benefit colorectal salamet kanker.
Pikeun nganalisis hubungan antara asupan serat sareng fana, panilitian kalebet 1575 pasién sareng tahap I nepi ka kanker koloréktal tahap I ti dua calon kohort; saatos nyaluyukeun pikeun prediksi salamet kanker poténsial anu sanés, spésifisitas kanker koloréktal ditangtukeun Kematian sareng total kematian.
Antara 6 bulan sareng 4 taun saatos diagnosis kanker koloréktal, panaliti ngagunakeun angket anu disahkeun dina frékuénsi tuang pikeun nganilai total asupan serat, jumlah serat tina sumber anu béda sareng jumlah gandum.
Among the 1575 participants, 963 (61.1%) were women; the average age was 68.6 years. With a median follow-up of 8 years, 773 patients died, of which 174 died from colorectal cancer. A high total fiber intake after diagnosis is associated with a lower mortality rate. For every 5g increase in daily intake, the multivariable HR for colorectal cancer specific mortality and all-cause mortality were 0.78 (95% CI 0.65 ~ 0.93; P = 0.006) and 0.86 (95% CI 0.79 ~ 0.93) P <0 .001). According to fiber sources, cereal fiber can reduce koloréktal cancer-specific mortality (for every 5 g / d increase in intake, HR = 0.67, 95% CI 0.50 ~ 0.90; P = 0.007) and all-cause mortality (HR = 0.78, 95% CI 0.68 ~ 0.90; P <0.001); vegetable fiber can reduce all-cause mortality (HR = 0.83, 95% CI 0.72 ~ 0.96; P = 0.009), but it does not reduce colorectal cancer-specific mortality (HR = 0.82, 95% CI 0.60 ~ 1.13; P = 0.22); No correlation was found between fruit fiber and mortality. Ingestion of whole wheat food can reduce the specific mortality of colorectal cancer (for every 20 g / d increase in intake, HR = 0.72, 95% CI 0.59 ~ 0.88; P = 0.002), but the correlation It will weaken after entry (HR = 0.77, 95% CI 0.62 ~ 0.96; P = 0.02).
