Cangkok sungsum tulang di India
Bone marrow stem cell transplants in India are performed by some of the leading cancer centres. To date, more than 10,000 successful bone marrow stem cell transplants have been performed in India. Patients from across the world visit India for bone marrow stem cell transplant.
Naon cangkok sél sirung tulang sungsum?
As per NCI dictionary of cancer terms bone marrow transplant is a procedure in which a patient receives healthy blood-forming cells (stem cells) to replace their own stem cells that have been destroyed by disease, radiation or high doses of anticancer drugs that are given as part of the procedure. The healthy stem cells may come from the bone marrow of the patient or a donor. A bone marrow transplant may be autologous (using a patient’s own stem cells that were collected from the marrow and saved before treatment), allogeneic (using stem cells donated by someone who is not an identical twin), or syngeneic (using stem cells donated by an identical twin). Also called BMT.
In simple terms when bone marrow is damaged or destroyed by disease, infection or chemotherapy then it is replaced by new stem cells which travels to the bone marrow where they produce new blood cells and promote growth of new marrow.
Sungsum tulang mangrupikeun bagian paling penting dina awak sareng nyiptakeun bagian-bagian getih ieu:
- sél getih beureum, anu mawa oksigén sareng nutrisi ka saluruh awak
- sél getih bodas, anu ngalawan inféksi
- trombosit, anu tanggel waler pikeun pembentukan gumpalan
Cangkok sungsum tulang ngagantikeun sél sirung rusak anjeun ku sél séhat. Ieu ngabantosan awak anjeun ngadamel sél getih bodas anu cekap, trombosit atanapi sél getih beureum pikeun nyingkahan inféksi, gangguan pendarahan, atanapi anémia.
Naha cangkok sél sirung tulang dilakukeun?
Bone marrow transplants, also knows as BMT, are performed when a patients marrow isn’t healthy enough to function properly. Some of the reasons of bone marrow transplant are :
- Anémia aplastik: in this disorder, the bone marrow stops making new blood cells.
- Cancers like leukemia, lymphoma & multiple myeloma affect the bone marrow badly.
- Sungsum tulang rusak sabab kémoterapi.
- Neutropenia bawaan, mangrupikeun kalainan anu diwariskeun anu nyababkeun inféksi anu teras-terasan
- Anémia sél sabit, nyaéta gangguan getih anu diturunkeun anu nyababkeun sél getih beureum anu misshapen
- Thalassemia is an inherited blood disorder where the body makes an abnormal form of hemoglobin, an integral part of red blood cells.
How is a bone marrow stem cell transplant performed?
Prior to bone marrow transplant, several tests are performed to determine what type of stem cells are required. There is a possibility that the patient undergo chemotherapy or radiation therapy to kill all the cancer cells or marrow cells before they get the new stem cells.
During the course of treatment, there is a huge vulnerability to immune system of the body. This causes the body to fight any kind of infections. Hence, patients are kept in a very special section of the hospital that’s reserved for people receiving bone marrow transplants.
The procedure of a bone marrow transplant is similar to that of a that of a blood transfusion.
If the patient is going for an allogenic transplant, bone marrow cells will be harvested from the donor a day or two before your procedure. If own cells are used, then they are retrieved from the stem cell bank.
During a bone marrow harvest, cells are collected from both hipbones through a needle. You’re under anesthesia for this procedure, meaning the patient will be asleep and free of any pain.
Leukaferesis
Leukapheresis is a process in which a donor is given five shots to help the stem cells move from the bone marrow into the bloodstream. Blood is then drawn through an intravenous (IV) line, and a machine separates out the white blood cells that contain stem cells.
A needle called a central venous catheter, or port, will be installed on the upper right portion of the patient’s chest. This allows the fluid containing the new stem cells to flow directly into the patient’s heart. The stem cells then disperse throughout the patient’s body. They flow through the patient’s blood and into the bone marrow. They’ll become established there and begin to grow.
The port is left in place because the bone marrow transplant is done over several sessions for a few days. Multiple sessions give the new stem cells the best chance to integrate themselves into the patient’s body. That process is known as engraftment.
Ngaliwatan palabuan ieu, anjeun ogé bakal nampi transfusi getih, cairan, sareng kamungkinan gizi. Anjeun panginten peryogi pangobatan pikeun merangan inféksi sareng ngabantosan sumsum énggal tumuh. Ieu gumantung kana kumaha anjeun ngatur pangobatan.
Salami waktos ieu, sabar diawaskeun pisan pikeun komplikasi naon waé.
Jinis cangkok sél sirung tulang sungsum
Aya dua jinis utama cangkok Sungsum Tulang. Jinis cangkok anu diperyogikeun gumantung kana alesan anu diperyogikeun BMT.
Tanduran Autologous
Autologous transplant use the own bone marrow to replace damaged stem cells. This is done by harvesting your cells before beginning a damaging therapy for them, like chemotherapy or radiation. However, this type of transplant can only be done if you have healthy bone marrow.
Cangkok palogén
Allogenic transplant is done when patient’s bone marrow is completely damaged and unable to function properly. This involves use of cells from the donor. Donor must be close genetic match. HLA typing test is conducted on the donors and patient and then it is matched. However, these patients have very high risk of complications, such as GVHD. Patient is also put on medications to suppress the immune system so that body doesn’t attack the new cells. The success of an allogenic transplant depends on how closely donor cells match the patient’s cells.
Komplikasi pakait sareng cangkok sél sirung tulang sungsum
Bone marrow transplant or BMT, is a major medical procedure and lot of precision and care is required along with requisite infrastructure in the hospital to carry out the procedure. One may experience following after BMT –
- turunna tekanan getih
- nyeri sirah
- seueul
- nyeri
- shortness tina napas
- chills
- muriang a
Salain ti anu ieu ogé tiasa janten sababaraha komplikasi anu sanés tapi sacara umum gumantung kana umur, kaséhatan sacara umum, panyakit anu parantos diubaran sareng jinis cangkok anu ditampi.
Kompléks tiasa hampang atanapi serius pisan, sareng aranjeunna
tiasa kaasup:
- panyakit tandur-lawan-host (GVHD), anu mangrupakeun kaayaan dimana sél donor nyerang awak anjeun
- kagagalan cangkok, anu lumangsung nalika sél anu ditransplantasi henteu ngamimitian ngahasilkeun sél anu anyar sakumaha anu direncanakeun
- ngaluarkeun getih dina bayah, uteuk, sareng bagian awak sanésna
- katarak, anu dicirikeun ku mendung dina lénsa panon
- karuksakan organ vital
- ménopause mimiti
- anémia, anu lumangsung nalika awak henteu ngahasilkeun cukup sél getih beureum
- inféksi
- seueul, diare, atanapi utah
- mucositis, nyaéta kaayaan anu nyababkeun peradangan sareng perih dina sungut, tikoro, sareng lambung.
Rumah sakit pangsaéna pikeun cangkok sél sirung tulang sumsum di India
- Rumah Sakit BLK, New Delhi
- Rumah Sakit Artemis, Gurugram, Delhi NCR
- Onkologi Amérika, Hyderabad
- Mazumder Shaw Narayana, Bangalore
- Rumah Sakit Khusus Narayana, Howrah
- Rumah Sakit Fortis, Gurgaon
- Institut Kanker Apollo, Hyderabad
- Institut kanker Apollo, Purwakarta
- Medanta médis, Gurgaon
- Rumah Sakit Dharamshila, Cirebon
Biaya cangkok sél sirung batang sumsum di India
An allogenic, fully matched bone marrow stem cell transplant in India cost approximately $ 25,000 USD di India.
Pertandingan satengahlogogic bakal ngarugikeun antara $29,000 jeung $35,000 USD
Cangkok sél bobot Aulogous bakal ngarugikeun antara $ 16,000 and $20,000 USD
Bone marrow stem cell transplant in India are commonly performed now. Patients from many countries like USA, UK, Europe, Africa, Bangladesh, Afghanistan, UAE etc now a days come to India for bone marrow stem cell transplant.
DOKTOR TERBAIK UNTUK BATU SUMBER TANGGAL SÉLÉN TRANSPLAN DI INDIA
Dr. Dharma Choudhary - Pusat Transplantasi Sungsum BLK, New Delhi nyaeta arguably dokter ngarah India pikeun sungsum tulang cangkok sél sirung kalawan leuwih ti 2000 transplants suksés ka kiridit na. Anjeunna dipikawanoh pikeun karir suksés na salaku dokter bedah luhur BMT, kaahlian Dr. Choudhary di Thalassemia Bone Sumsum Transplant, Thalassemia Stem Cell Transplant. Dr Dharma Choudhary nyaéta panaratas di India pikeun karyana dina Transplantasi Sumsum Tulang Allogenic pikeun Thalassemia Mayor jeung Anemia Aplastic salila periode na di Rumah Sakit Sir Ganga Ram Cirebon. Dr Dharma Choudhary parantos dugi ka daptar top 10 Hematologists sareng Spesialis Transplantasi Sumsum Tulang generasi ieu di India. Dipikawanoh pikeun tingkat kasuksésan anu luhur dina Transplantasi Sumsum Tulang, Dr. Dharma Choudhary mangrupikeun anggota saumur hirup tina India Society of Hematology & Transfusion Medicine. Anjeunna ogé populer di kalangan pasien internasional ti pelosok dunya anu lolobana ti Afghanistan, Irak, Oman, Uzbekistan, Sudan, Kenya, Nigeria, sareng Tanzania.
Dr Sanjeev Kumar Sharma mangrupikeun ahli latihan Hematologis kalayan pangalaman 19 taun. Anjeunna aya di New Delhi. Dr Sanjeev Kumar Sharma latihan di Rumah Sakit BLK Super Khusus di New Delhi. Rumah Sakit BLK Super Khususna aya di 5, Radha Soami Satsang Rajendra Place, Pusa Road, New Delhi. Sanjeev Kumar Sharma mangrupikeun anggota anu terhormat tina anggota Kadaptar India Society of Hematology and Blood Transfusion (ISHTM), anggota anu didaptarkeun di Association Medical Médis (DMA) Anggota anu didaptarkeun India Society of Hematology and Blood Transfusion (ISHTM), anggota anu didaptarkeun di Delhi Medical Association ( DMA) sareng Anggota Masarakat India pikeun Panalitian Atherosclerosis (ISAR).
Anjeunna ngudag MBBS na dina taun 1999 ti University Of Delhi, Cirebon. Anjeunna réngsé MD dina taun 2006 ti University Of Delhi, Cirebon. Anjeunna ogé parantos ngalaksanakeun DM na dina taun 2012 ti All India Institute Of Medical Medical, New Delhi.
.Dr Sanjeev parantos dilélér sareng Best Citizen of India Award.
Dr Revathi Raj mangrupikeun Hematologist sareng Pediatrik di Rumah Sakit Apollo, Teynampet, Chennai sareng gaduh pangalaman 24 taun dina bidang ieu. Dr Revathi Raj latihan di Rumah Sakit Kanker Khusus Apollo di Teynampet, Chennai sareng Rumah Sakit Barudak Apollo di Rébuan Lampu, Chennai. Anjeunna réngsé MBBS ti Madras University, Chenai, India di 1991, Diploma Health Child (DCH) ti The Tamil Nadu Dr. MGR Medical University (TNMGRMU) di 1993 sareng FRC.PATH. (UK) ti The Royal College of Pathologist di 2008 Anjeunna mangrupikeun anggota Asosiasi Médis India (IMA). Sababaraha layanan anu disayogikeun ku dokter nyaéta: Perawatan Eosinofilia, Perawatan Nyeri Beuheung, Terapi Chelation, Biokimia sareng Transfusi Darah sareng sajabana Dr Revathi dikredit sareng salah sahiji séri pangageungna dina cangkok sungsum tulang di nagara éta. Anjeunna parantos suksés ngubaran hémofilia & panyakit sél arit. Anjeunna ngagaduhan minat khusus pikeun gangguan getih di murangkalih.
Dr Sharat Damodar - Narayana Bone Marrow Transplant Center, Bangalore Dr Sharat Damodar ngarengsekeun MBBS na ti St. Johns Medical College, Bangalore sareng saatos réngsé MD-na ti kuliah DNB. Anjeunna ayeuna damel salaku Wakil Présidén Pusat Médis Mazumdar Shaw, Kota Kaséhatan Narayana. Anjeunna mangrupikeun ahli Onkologi sohor anu parantos ngalaksanakeun langkung ti 1000 Tulang Sungsum & Cangkok Sél Stem sareng ogé kéngingkeun Penghargaan Pimpinan pikeun Dokter Pangsaéna di 2015. Widang kaparigelan Dr. Sharat nyaéta sumsum tulang & cangkok sél sirung, cangkok getih ari & limfoma. Prosedur konci anu dilakukeun ku Dr. Sharat Damodar nyaéta Tulang sungsum & cangkok sél sirung, cangkok getih ari, leukemia / limfoma. Dr Sharat parantos ngalaksanakeun langkung ti 1000 suksés cangkok sél sirung tulang dina karirna dugi ka ayeuna.
Dr Ramaswamy NV at Aster Medcity, Kochi is a Hematologist with more than 18 years of experience, Dr. Ramaswamy is an expert in management of malignant and non-malignant diseases of the blood, in patients of all ages. His areas of special interest are hemato oncology and stem cell transplant. Dr. Ramaswamy is expert in bone marrow stem cell transplant, prostate cancer, lung cancer, stomach cancer, colon cancer, & blood related disorders. He is specially interested in immunosuppressive drugs, targeted therapy, hodgkins lymphoma, myeloma, lymphoma, strocytoma, osteosarcoma, stereotactic radiosurgery, blood cancer, leukemia, sickle-cell anemia, germ cell tumour (GCT), thalassemia, non hodgkin lymphoma, and all forms, type and stages of cancer.
Dr. Pawan Kumar Singh - Artemis, Gurugram, Delhi (NCR) nyaéta ngalaman pangalaman ngalaksanakeun langkung ti 300 cangkok sungsum tulang (kalebet Autologous / Allogenic / Haplo / MUD) pikeun gangguan getih anu ganas sareng sanés anu malignant kalebet thalassemia sareng anémia aplastic. Rengse Haplo BMT suksés pikeun SCID dina budak umur 8 bulan. Suksés dilakukeun MFD BMT pikeun HLH dina budak yuswa 2 taun.
Sacara individual nyetél unit BMT di Rumah Sakit Jaypee sareng ngadamel SOP pikeun tiap-tiap léngkah penting pikeun hasil ngajalankeun unit BMT. Dijieun BMT UNIT di rumah sakit Jaypee pusat transplantasi pikeun cangkok MUD sareng ngagaduhan produk PBSC ti nasional (Datri) sareng pendaptaran internasional (DKMS).
Dilaksanakeun 50 BMT dina 18 bulan terakhir di rumah sakit Jaypee (MSD / MFD-20; Haplo-6; Otomatis-2 sareng MUD-4).
Dr Joydeep Chakrabartty - Kolkata réngsé MBBS na ti universitas terkenal di Kalkuta sareng teras angkat ka Inggris pikeun kuliah pascasarjana. Anjeunna teraskeun kéngingkeun Kapercayaan MRCP (Inggris) sareng FRC PATH (Inggris), sareng FRCP (Glasgow) salami karirna. Anu terakhir dibales pikeun kalungguhanana dina mingpin sareng netepkeun jasa di Kedokteran. Anjeunna ngagaduhan minat khusus di daérah Panyebaran Sungsum Tulang (BMT), khususna cangkok tungtung luhur anu cocog pikeun sadaya kaayaan khususna Leukemias Akut. Anjeunna parantos damel di lembaga terkenal di Inggris kalebet Rumah Sakit St Bartholomews sareng di Bone Marrow Transplant Fellowship anu bergengsi di The Imperial College, Rumah Sakit Hammersmith, London.
Dr Joydeep Chakrabartty parantos damel mangtaun-taun di Kedokteran sareng di unit perawatan Kritik anu terkenal sateuacan nyandak Hematology. Anjeunna parantos pendak sareng ngatur henteu ngan ukur sadayana kaayaan darurat sareng kaayaan hématologis tapi ubar umum na sareng paparan ICU sateuacanna masihan pangatur pasien anu gering pisan nyaéta pasién anu ngalaman cangkok sungsum tulang, Leukemia akut sareng sajabana Anjeunna ogé kompeten pisan dina bagian diagnostik laboratorium tina panyakit hématologis. Nalika balikna, Dr. Chakrabartty ngabantosan dina formasi sareng suksés ngajalankeun seueur departemén Transplantasi Sungsum di seluruh negeri. Dr Joydeep Chakrabartty parantos nyerat seueur tulisan pikeun jurnal unggulan sareng ogé nyerat bab dina buku téks.
Dr Radheshyam Naik at Bangalore mangrupikeun panaratas dina bidang Médis Onkologi kalayan langkung ti 25 taun pangalaman akademik anu kuat dina bidangna. Anjeunna nampi pelatihan lanjutan ti lembaga terkemuka di dunya kalebet MD Anderson Cancer Institute, USA, International School for Cancer Care, Oxford, UK, University of New South Wales, Australia, pikeun nyebatkeun sababaraha.
Dianggap salaku ahli onkologi terkenal sareng gaduh pangalaman nganjang ka rumah sakit kanker anu terkenal di panjuru dunya, Dr. Radheshyam parantos ngagaduhan karir akadémik anu hadé dina ngatur sagala jinis kanker sareng gangguan haematologis, kalayan sababaraha publikasi anu ditinjau tara dina jurnal unggulan. Anjeunna mangrupikeun panaratas dina ngalaksanakeun sababaraha uji coba Narkoba anu dilakukeun langkung ti 50 ubar kémoterapi dina uji coba nasional sareng internasional.
Anjeunna ngagaduhan minat khusus kana program Transplantasi Sungsum Bone sareng ogé ngalaman palatihan canggih di Hadassah University, Israel; Pusat médis Detroit, rumah sakit New York AS, pusat Médis Cornell sareng di Rumah Sakit Harper, Michigan, AS.
Dr Radheshyam parantos janten kontributor utama dina ngembangkeun bidang Hematology sareng Transplantasi Sungsum Tulang di Karnataka. Anjeunna ngalaksanakeun kémoterapi intra-artéri anu munggaran ngalangkungan palabuan di Karnataka sareng ogé diakui pikeun ngalakukeun Tangkal Sungsum Tulang munggaran di Karnataka.
Dr. Shrinath Kshirsagar nyaéta hematologist / hemato-oncologist sareng dokter cangkok sungsum tulang dumasar di Sukabumi. Anjeunna gaduh pangalaman langkung ti 8 taun dina bidang ieu. Anjeunna parantos réngsé latihan super-istiméwa ti Pusat Médis Tata anu bergengsi. Anjeunna mangrupikeun bagian tina tim anu ngalakukeun langkung ti 200 cangkok sungsum tulang salami dua taun. Anjeunna gaduh seueur terbitan nasional sareng internasional. Anjeunna panaliti prinsip dina salah sahiji sidang klinis dina bidang leukemia. Prosedur utama anu dilakukeun ku Dr. Srinath nyaéta sungsum tulang & cangkok sél sirung, cangkok getih ari, leukemia / limfoma. Kamajuan anu signifikan parantos dilakukeun pikeun maham biologi Leukemia salami sababaraha dasawarsa ka tukang. Ieu parantos ditarjamahkeun pikeun pangakuan target novél pikeun terapi, pilihan terapi novél sareng terapi anu ditargét anu dina gilirannana sacara signifikan ningkatkeun hasil klinis pasien Leukemia. Dr Shrinath Shirsagar nyaéta dokter anu berpengalaman pikeun Leukemia sareng Lymphoma anu canggih di Kota Sukabumi. Kalayan pangalaman 8 taun Anjeunna resep pisan kana ubar imunosupresip, terapi sasar, limfoma hodgkins, myeloma, limfoma, strocytoma, osteosarcoma, radiosurgery stereotaktik, kanker getih, leukemia, anémia sél arit, tumor sél kuman (GCT), talasemia, limfoma non hodgkin, sareng sadaya bentuk, jinis sareng tahapan kanker.
