Daraasad cusub ayaa muujineysa taas bukaanka qaba beerka ama beerka-xukuma kansarka mindhicirka ee metastatic , Ku darida daaweynta shucaaca gudaha ee xulashada safka koowaad ee mFOLFOX6 kiimoterabiga ayaa keenaya koror weyn oo badbaadada bukaanada qaba burooyinka asaasiga ah ee midigta.
SIRT, oo laga isticmaali jiray Yurub ilaa 2003, waa a shucaaca gudaha isticmaalaya Y-90 microspheres cusbi (dhexroor u dhexeeya 20 iyo 60 mikroonoron) lagu keenay xididka halbowlaha iyadoo la isticmaalayo tuubada . Beta shucaaca sii deynaya microspheres ayaa doorbidey in lagu meeleeyo microvessels agagaarka burooyinka, iyadoo la yareynayo saameynta nidaamka.
Daraasadaha caalamiga ah ee SIRFLOX, FOXFIRE iyo FOXFIRE waxaa looga dan lahaa in lagu qiimeeyo waxtarka iyo badbaadada SIRT oo lagu daray kiimikada ugu horeysa ee loo yaqaan 'oxaliplatin chemotherapy' ee loogu talagalay mCRC oo aan la xakamayn karin.
Bukaannada 554 ee helay kemotherabi oo lagu daray SIRT iyo 549 bukaan ah oo helay kiimoteraabiga oo keliya, natiijooyinka waxay muujiyeen in waqtiga badbaadada ee dhexdhexaadka ah ee burooyinka bidix ee bukaanada mCRC ee ku jira kemotherabi oo lagu daray kooxda SIRT ay ahayd 24.6 bilood, marka la barbar dhigo 26.6 bilood ee kooxda keliya ee kemotherabi. , laakiin SIRT kiimoteraabiga Badbaadada dhexdhexaadka ah ee bukaanada mCRC ee leh burooyinka hal dhinac ah waxay ahaayeen 22 bilood kooxda iyo 17.1 bilood kooxda kaliya ee kiimoteraabiga, oo ahayd 5 bilood dheer.
Shir jaraa'id, Dr. Harpreet Wasan wuxuu u sheegay Imperial College Health Care NHS Trust ee UK in mala awaalku yahay in kansarka dhinaca midig kaliya uusan […] ka sii darin laakiin uu yahay mid iska caabiya daaweynta kiimoteraabiga. Waxay u nuglaan karaan daaweynta shucaaca, oo leh qaab ficil ahaanba gebi ahaanba ka duwan.
Dr. Wasan ayaa intaa ku daray in la'aanta natiijooyinka wanaagsan ee falanqaynta guud ay sababi karto in lagu daro bukaanada qaba kansarka ba'an ee ka baxsan beerka. Wuxuu yiri: "Inkastoo SIRT ay xakameyn karto cudurrada beerka, ma xakamayn karto cudurrada ka baxsan beerka."
