Daraasada ugu weyn ee genome-wide kansarka guud ee kansarka ilaa maanta, cilmi baarayaal ka tirsan Xarunta Kansarka ee Johns Hopkins Kimmel iyo Machadka Qaranka ee Kansarka iyo la shaqeeyeyaasha in ka badan 80 hay'adood oo kale oo adduunka ah waxay ogaadeen isbadal ku dhaca shan gobol oo cusub oo hiddo-wadaha aadanaha Tani waxay kordhin kartaa halista kansarka ganaca.
Daahfurka waxaa lagu daabacay Isgaarsiinta Dabeecadda Febraayo 8, saynisyahannaduna waxay falanqeeyeen in ka badan 11.3 milyan oo isbeddel ah 21,536 qof. Daahfuradan cusubi waxay keeneen talaabo kale oo lagu xirayo isbedelada hidaha ee laxiriira arrimaha halista kansarka ganaca, taas oo sifiican u fahmi karta cudurka kansarka beeryarada waxayna hagaysaa cilmi baarista habab badan oo daaweynta loola dan leeyahay iyo ogaanshaha hore iyo hababka baaritaanka. Noocyada hiddo-wadaha cusub ee lagu aqoonsaday koromosoomyada aadanaha 1 (booska 1p36.33), 7 (booska 7p12), 8 (booska 8q21.11), 17 (booska 17q12), iyo 18 (booska 18q21.32) waxay kordhiyaan halista kansarka ganaca. Jiritaanka nuqul kasta oo ku jira genomes-kan wuxuu kordhiyaa halista kansarka ganaca 15-25%.
Heerka shaqsiyeed, waxaa jira isbedel aan gebi ahaanba saadaalin karin kansarka, maxaa yeelay waxay kaliya la xiriiraan isbeddel yar oo khatar ah, laakiin markii la isku daro, waxay gacan ka geystaan sidii si buuxda loogu fahmi lahaa cudurka kansarka ganaca. Baarayaasha waxay sii wadi doonaan inay kudarsamaan astaamaha hidde ee kansarka ganaca, waxaana jira waxyaabo badan oo hidde ah oo aynaan ka ogayn halista kansarka ganaca.
Fahamka habka isbeddelka hidda-wadaha ee kansarka ganaca ayaa si fiican u horumarin kara dawooyinka la bartilmaameedsado, kuwaas oo dejin doona mowjadaha daaweynta kansarka ganaca. Waxaa jira dawooyin badan oo lala beegsaday suuqa oo loogu talagalay kansarrada kale. Noocyada kala duwan ee hiddo-wadaha mutant, daawooyinka la beegsaday ayaa loo isticmaalaa si loo yareeyo waxyeellooyinka iyo hagaajinta waxtarka. Sidaa darteed, waxaa lagula talinayaa in bukaannada kansarku ay fiiro gaar ah u yeeshaan booska faa'iidada ee daaweynta la beegsanayo oo ay sameeyaan baaritaanka hidda-socodka ka hor daawada.
Shirkadaha waaweyn ee awooda leh ee dooran kara inay sameeyaan baaritaanka hida-sidaha kansarka waa American Kerrys, American Foundation, kuwa gudahana waxay leeyihiin Pansheng, Shihe Gene. Shabakada Caalamiga ah ee Oncologist waxay ka caawin kartaa bukaanada baaritaanka hidda-socodka inta lagu jiro hawsha. Bukaanku waxay la tashan karaan Shabakada Global Oncologist Network si ay ula tashadaan.
Tixraac: https://medicalxpress.com/news/2018-02-genetic-linked-pancreatic-cancer.html
