Kansarka ganaca ayaa hadda ah mid ka mid ah kansarka ugu dhimashada badan ee u adkaysta kiimoterabiga. Dhawaan, cilmi-baarayaasha kansarka ee Australiya waxay soo saareen hab nanomedical ah oo rajo leh oo wanaajin doona daaweynta kansarka ganaca.
Farsamadan waxay soo duubtaa dawooyinka aamusin kara hiddo-wadaha gaarka ah ee nanoparticles oo u gudbiya burooyinka ganaca . Waxa la filayaa in ay siiso bukaanada kansarka ganaca ku jira beddelka daawaynta dhaqameed sida kiimoterabiga.
Experiments conducted on mice showed that the new nanomedicine method reduced buro growth by 50% and also slowed the spread of pancreatic cancer.
Cilmi-baarista lagu daabacay Biomacromolecules waxaa sameeyay saynisyahanno ka socda Jaamacadda New South Wales (UNSW). Waxay rajo cusub u keentaa bukaanjiifka kansarka ganaca badankood ee noolaan kara kaliya 3-6 bilood kadib ogaanshaha cudurka.
Dr. Phoebe Phillips oo ka socota Xarunta Cilmi-baarista Kansarka ee UNSW ee Roy (Xarunta Cilmi-baarista Kansarka Lowy) ayaa ahayd qofka ugu weyn ee mas'uulka ka ah daraasadda. Waxay sheegtay in mar kasta oo asxaabteeda takhaatiirta ay ku qasbanaadeen inay ku wargeliyaan bukaannada kansarka ganaca, Xataa haddii dawooyinka kemotherabi ee ugu wanaagsan ay kaliya ka caawin karaan inay noloshooda kordhiyaan 16 toddobaad, dhakhaatiirtu runtii waa kuwo aan loo dulqaadan karin.
Dr. Phillips waxa uu yidhi: “Sababta ugu weyn ee daawaynta kiimikaad u shaqayn wayday waa in burooyinka ganacadu ay leeyihiin unug nabarro badan oo kala duwan, kuwaas oo 90% ka noqon kara dhammaan burada. Unugyada nabartu waxay u dhaqmaan sidii xannibaad jireed oo ka hortagaya daawooyinka inay gaaraan burada, taasoo keenta kansarka ganaca. Unugyadu waxay u adkaystaan daweynta kiimoterabiga. "
She explained: “Recently, we have discovered a key gene that promotes the growth, spread and resistance of xayawaanka cancer-βIII-tubulin. Inhibiting this gene in mice not only reduced tumor growth by half, It also slows down the spread of cancer cells. “
Si kastaba ha noqotee, si loo xakameeyo hidda-socodkan bukaan-socod ahaan, qofku waa inuu ka adkaadaa dhibaatada maamulka daroogada: ka gudubka unugyada nabarrada ee burooyinka ganaca . Si loo xaliyo dhibaatadan, cilmi-baarayaasha Australiyaanka ah waxay soo saareen hab nano-caafimaad ah, molecules RNA yar yar (waxaa loo fahmi karaa nuqul ka mid ah DNA-da gacanta) oo lagu duudduubay nano-particles horumarsan, molecules RNA waxay gaaraan burada ka dib marka ay awoodaan xad weyn, waxay joojisaa hidda-wadaha βIII-tubulin.
Cilmi-baarayaashani waxay muujiyeen suurtagalnimada nanoparticles cusub ee jiirarka. Nanoparticles-yadooda waxay gaarsiin karaan qiyaaso daweyn oo microRNA ah burooyinka ganaca ee jiirarka iyadoo ay joogaan unug nabar ah, waxayna si guul leh u joojiyaan βIII-tubulin.
"Ahmiyadda tignoolajiyada nanomedicine-ka ayaa ah in la filayo in la xakameeyo hidde-side kasta oo buro kor u qaada, ama hiddo-sideyaal 'si gaar ah loo habeeyey' oo ku salaysan muujinta hidda-wadaha buka." Dr. Phillips ayaa yiri.
Guushan ayaa dadka ka caawin doonta inay soo saaraan daaweyn cusub oo kansar ah oo u adkaysta kansarka waxayna xoojineysaa waxtarka hababka daaweynta kiimikada ee hadda jira, taas oo kor u qaadeysa heerka badbaadada iyo tayada nolosha bukaannada kansarka beeryarada.
