Mingyang Song ee Dugsiga Caafimaadka Harvard iyo Isbitaalka Guud ee Massachusetts ayaa sheegay in ka dib marka la ogaado kansarka mindhicirka ee aan metastatic ahayn, in la cuno fiber badan ay yarayn doonto dhimashada gaarka ah iyo guud ahaan dhimashada kansarka mindhicirka. Kordhinta qaadashada fiber ka dib ogaanshaha cudurka waxay ka faa'iideysan kartaa bukaanka qaba kansarka malawadka. (JAMA Oncol. Nooca khadka tooska ah ee Nofeembar 2, 2017).
Although it has been shown that high dietary fiber intake reduces the risk of colorectal cancer, it is not clear whether high fiber intake will benefit colorectal ka badbaaday kansarka.
Si loo qiimeeyo xiriirka ka dhexeeya qaadashada fiber-ka iyo dhimashada, daraasadda waxaa ka mid ahaa bukaanno gaaraya 1575 oo qaba heerka XNUMX-aad ilaa III kansarka mindhicirka ee ka imanaya laba wada-jir mustaqbalka ah; kadib markii loo hagaajiyay saadaaliyayaasha kale ee badbaadada kansarka, gaar ahaanta kansarka mindhicirka waxaa la go'aamiyay Dhimashada iyo geerida guud.
Inta udhaxeysa 6 bilood ilaa 4 sano kadib ogaanshaha cudurka kansarka malawadka, cilmi baarayaashu waxay isticmaaleen su'aal la ansaxiyay oo ku saabsan inta jeer ee la cuno si loo qiimeeyo wadarta qaadashada fiberka, qadarka faybarka laga helo ilo kala duwan iyo qadarka qamadiga oo dhan.
Among the 1575 participants, 963 (61.1%) were women; the average age was 68.6 years. With a median follow-up of 8 years, 773 patients died, of which 174 died from colorectal cancer. A high total fiber intake after diagnosis is associated with a lower mortality rate. For every 5g increase in daily intake, the multivariable HR for colorectal cancer specific mortality and all-cause mortality were 0.78 (95% CI 0.65 ~ 0.93; P = 0.006) and 0.86 (95% CI 0.79 ~ 0.93) P <0 .001). According to fiber sources, cereal fiber can reduce colorectal cancer-specific mortality (for every 5 g / d increase in intake, HR = 0.67, 95% CI 0.50 ~ 0.90; P = 0.007) and all-cause mortality (HR = 0.78, 95% CI 0.68 ~ 0.90; P <0.001); vegetable fiber can reduce all-cause mortality (HR = 0.83, 95% CI 0.72 ~ 0.96; P = 0.009), but it does not reduce colorectal cancer-specific mortality (HR = 0.82, 95% CI 0.60 ~ 1.13; P = 0.22); No correlation was found between fruit fiber and mortality. Ingestion of whole wheat food can reduce the specific mortality of colorectal cancer (for every 20 g / d increase in intake, HR = 0.72, 95% CI 0.59 ~ 0.88; P = 0.002), but the correlation It will weaken after entry (HR = 0.77, 95% CI 0.62 ~ 0.96; P = 0.02).
