Kansarka Pankreatic
Pancreatic cancer is a malignant tumor of the digestive tract that is highly malignant and difficult to diagnose and treat. About 90% is ductal adenocarcinoma that originates in the ductal epithelium. Its morbidity and mortality rates have increased significantly in recent years. The 5-year survival rate is <1%, which is one of the malignant tumors with the worst prognosis. The early diagnosis rate of kansarka ganaca is not high, the surgical mortality is high, and the cure rate is very low. The incidence of this disease is higher in males than in females , with a male to female ratio of 1.5 to 2: 1. Male patients are much more common than premenopausal women. Postmenopausal women have similar incidences as men.
Ayaa halis weyn ugu jira kansarka ganaca?
Sababtoo ah kansarka beeryaradu waxay u badan yihiin dadka da'da dhexe iyo kuwa da'da ah, badanaa waxay leeyihiin taariikh sigaar cabbineed, sidaas darteed waa inay fiiro gaar ah u yeeshaan joojinta sigaarka, si gaar ah u taxaddaraan waxyeelada sigaarka gacan labaad, iyo in la yareeyo tirada goobaha sida shatariga. iyo qolalka kaararka. Waxaa la og yahay in cabbitaanka badan uu sidoo kale waxyeello u geysto beeryarada, waana in fiiro gaar ah loo yeesho joojinta cabbitaanka, daawaynta waqtigeeda ee degdega ah iyo kuwa dabadheeraada ee pankreatit iyo biliary tract, sidoo kale dadka qaba H.pylori waa in la daaweeyaa waqtigeeda.
Samee caadooyin cunno caafimaad leh, cun cunno dufan badan, kaloriin badan, sigaar cabbin iyo solay cuntooyinka shiilan, cun afar lugood (lo ', adhi, doofaar), cun labada lugood (digaag, duck, goose)) iyo haley) cunto, cun cuno badarro qalafsan, khudaar iyo miraha, gaar ahaan cun broccoli, khudradda iskutallaabta ah (khudaarta cagaaran), oo ay kujiraan walxaha isothiocyanate, waxay kahortagi kartaa walxaha kiimikada ee Dhaawacyada DNA iyo burooyinka kaladuwan.
U hoggaansamo jimicsi jireed dhexdhexaad ah, dhaqdhaqaaqyada hawada hawada dibadda ee qorraxda waxay kor u qaadi karaan jirka si uu u soo saaro borotiinno isku xiran. Borotiinka isku xidha waxa uu leeyahay saamayn anti-oxidation iyo anti-buro.
Intaa waxaa dheer, shaaha cagaaran wuxuu kaloo ka kooban yahay maaddooyin ka-hortagga oksaydhka waana in si joogto ah loo cuno.
Kooxaha halista badan:
1. Da'da ka weyn 40 sano, oo leh raaxo-darro caloosha sare ah oo aan gaar ahayn.
2. Taariikh qoys oo ku saabsan kansarka ganaca.
3. Sonkorowga degdega ah, gaar ahaan cudurka macaanka aan caadiga ahayn, oo ka weyn 60 sano, la'aanta taariikhda qoyska, cayil la'aan, oo si dhakhso ah u yeeshaan caabbinta insulinta. 40% bukaannada kansarka qanjidhada ku dhaca waxaa laga helay cudurka macaanka.
4. Cudurka beeryarada ee daba-dheeraada bukaanka. Waqtigan xaadirka ah, xanuunka loo yaqaan 'pancreatitis chronic' waa nabar muhiim ah oo ku dhaca bukaano tiro yar, gaar ahaan qamriga joogtada ah ee qoysaska iyo kalgacalka joogtada ah.
5. Myxoma papillary intraductal sidoo kale waa dhaawac horay u soo gaadhay.
6. Kuwa la socda polyposis adenomatous qoys.
7. Kuwii la soo maray gastrectomy fog dhaawacyada aan fiicnayn, gaar ahaan kuwa in ka badan 20 sano qalliinka kadib.
8. Sigaar cabbista muddada dheer, cabbidda badan, iyo soo-gaadhista muddada dheer ee kiimikooyinka waxyeellada leh. The risk factors for pancreatic cancer are complex, with endogenous (family history, genetic mutation) and exogenous (environment, diet and other factors). A study published in the journal Nature in 2010 pointed out that normal pancreatic ductal epithelial cells gradually evolve into cancer. It takes 9 years from genetic mutation to the formation of a real buro cell, 8 years from the development of a tumor cell to a cell mass with metastatic ability, and the death from tumor discovery to tumor is less than 2 years. Therefore, the adverse factors that cause cell malignancy should be avoided as much as possible to prevent the occurrence of pancreatic cancer.
1. Sigaar cabidda: Waxaa hadda loo aqoonsaday inay tahay cunsur halis sare ugu jirta kansarka ganaca. Daraasaduhu waxay muujiyeen in saamiga halista ee sigaar cabista bukaanjiifka kansarka ganaca ku dhaca ee dadka aan sigaarka cabi ay tahay 1.6-3.1: 1. Daraasado la sameeyay ayaa muujisay in kansarka ku jira caleemaha tubaakada uu sababi karo kansarka qanjirka ganaca epithelium.
2. Cunto aan caafimaad qabin: Hay'adda Cilmibaarista Kansarka Adduunka iyo Machadka Kansarka ee Mareykanka ayaa soo koobay xiriirka ka dhexeeya cuntada iyo kansarka ganaca. Waxaa la rumeysan yahay in cuntooyinka hodanka ku ah hilibka guduudan (doofaarka, lo'da, wanka), dufanka badan iyo tamarta sareysa ay kordhin karaan halista kansarka ganaca, iyo qaadashada cunno ay ku badan yihiin khudaarta iyo miraha ayaa ka hortagi kara 33% ilaa 50% xammeetida kansarka Cudurka
3. Sababaha hidaha Dhacdooyinka kansarka ganaca ayaa 3-13 jeer ka badan dadka leh taariikh qoys marka la barbar dhigo kuwa aan lahayn taariikh qoys. Waxaa la soo sheegay in hal qof oo qoyska ka mid ah uu qabo cudurka, halista kansarka ganaca ku dhaca ee xubnaha kale ee qoysku waa 4 jeer marka loo eego tirada guud ee dadweynaha Haddii 2 qof ay xanuunsadaan, waxay ku sii kordheysaa 12 jeer, 3 qofna waa u kacayaan 40 jeer. Baarayaasha qaar waxay la kulmeen qoysas fara badan oo kansarka xammuulka ah oo hooyo iyo gabadh ah, aabbe iyo wiil, walaalo, iyo ayeeyo.
4. Dhaawacyada joogtada ah ee xammeetida: Dhacdooyinka soo noqnoqda ee ganaca joogtada ah, dhagxaanta duleelka ganaca ama kalgacalaha samaysan ayaa leh u janjeera inay noqdaan kansar, waxaana loo qaadan karaa inay tahay dhaawac horay u soo gaadhay. Feejignaanta waa in la siiyaa daaweynta cudurka aasaasiga ah waana in dabagal lagu sameeyaa si dhow. Bilowgu wuxuu kaloo laxiriiraa cudurada jirka bina aadamka, sida xanuunada joogtada ah ee ganaca iyo afka.
5. Sonkorowga: Daraasadu waxay ogaatay in bukaanada sonkorowga qaba ay laba jibbaar u leeyihiin kansarka ganaca (pancreatic cancer) sida dadka caadiga ah. Dhacdooyinka sonkorowga ee bukaanka kansarka beeryarada ayaa ku dhowaad laba jibaar ka badan dadka caadiga ah. Sidaa darteed, bukaanada aan lahayn taariikh qoys ee sonkorowga waxay si lama filaan ah u ogaadaan inay tahay in si taxadar leh loo hubiyo si looga saaro kansarka ganaca.
6. Cudurka qanjirka 'pancreatic burada' Sida xubnaha kale, xammeetidu waxay kaloo leedahay burooyin aan dhib badnayn. Tusaale ahaan: serous or mucinous cystadenoma, buro adag oo pseudopapillary, intraductal mucinous papilloma, iwm, oo waliba loo badali karo kansarka ganaca, qaasatan mucinous papilloma iyo intraductal mucinous papilloma.
7. Cudurada afka: Studies have shown that dental caries and other oral inflammatory diseases can also increase the incidence of xayawaanka kansarka.
8. Kuwa kale: Bukaannada qaba qoysaska loo yaqaan 'adenomatous polyposis', dhaawacyo aan fiicnayn oo ku dhaca caloosha 'gastrectomy distal', 'biliary tract disease', qalliinka xameetida, iyo Helicobacter pylori positive ayaa sidoo kale kordhin doonta halista kansarka ganaca.
