Daraasad cusub ayaa qeexaysa xiriirka ka dhexeeya thecytokine interleukin-1β(IL-1β) iyo buurnaanta. Marka heerarka IL-1β ay kordhaan buurnaanta, firfircoonida calaamadaha IL-1receptor waxay keenaysaa tiro badan oo kansar mindhicir ah. Noocyada siyaabo. Daraasadani waxay muujinaysaa in buurnida xad dhaafka ah ay la xiriirto kororka nidaamka ee IL-1β, firfircoonida Wnta iyo kororka unugyada xiidmaha jiirka.
Joel Mason oo ka tirsan Jaamacadda Tufts ee Massachusetts iyo Tufts University School of Medicine iyo asxaabtii kale ee Jaamacadda Tufts ayaa si wada jir ah u qoray maqaalka ”Interleukin- 1 Ishaajinta Dhexdhexaadinta Cayilka-Dhiirrigelinta Kordhinta Cudurka 'Cytokines', Waxqabadka Wnt, iyo Yar" Faafitaanka unugyada epithelial jiirka colonic " . “
Cilmi-baadhayaashu waxay dejiyeen si ay u go'aamiyaan doorka IL-1β ee habaynta dhacdooyinka u horseedaya cayilka-kor u qaada kansarka mindhicirka. Waxay barbar dhigeen doorka IL-1β ee jiirarka quudiyay cunto dufan badan ( buuran) ama dufan yar (cataa) ah. Mid ka mid ah isbeddelada laga helo jiirarka buuran ee leh xuubka mindhicirka 30-80 % fiirsashada sare ee IL-l [beta], Wnt cascade waxay si weyn u kordhisay kor u qaadida calaamadaha waxayna si weyn ugu badineysaa crypts gobolka xiidanka.
"Daraasadani waxay muujineysaa xiriirka dhow ee ka dhexeeya cayilka iyo jawaab celinta caabuqa, waxayna ka tarjumaysaa doorka ballaaran ee IL-1β, oo qeexaya cayilku inuu yahay mid ka mid ah cudurro badan oo caabuq badan," Waaxda Immunology, Jaamacadda Washington, Xarunta Difaaca Innate iyo Cudurada Difaaca. Michael Gale Jr, oo ah tifaftiraha guud ee joornaalka 'Interferon & Cytokine Research' ayaa yiri.
