Mune yakakura genome-yakafara pancreatic cancer kudzidza kusvika parizvino, vaongorori paJohns Hopkins Kimmel Cancer Center neNational Cancer Institute uye vanobatana mune anopfuura makumi masere mamwe masangano pasi rese vakawana shanduko mumatunhu mashanu matsva ejenome remunhu Izvi zvinogona kuwedzera njodzi. chirwere chepancreatic.
Kuwanikwa uku kwakaburitswa muEnline Communications munaFebruary 8, uye masayendisiti akaongorora zvinopfuura mamirioni gumi nemakumi matatu nematanhatu muvanhu 11.3. Izvi zvitsva zvakawanikwa zvakakurudzira rimwe danho mukubata shanduko yemaronda inosanganisirwa nekenza yepancreatic njodzi, izvo zvinogona kunzwisisa zviri nani pathogenesis yekenza yepancreatic uye inotungamira kutsvagurudzwa kwenzira dzakanangwa dzekurapa uye nzira dzekutanga kuona uye kuongorora. Ichangobva kuzivikanwa mageneti akasiyana pamakromosomes evanhu 21,536 (chinzvimbo 1p1), 36.33 (chinzvimbo 7p7), 12 (chinzvimbo 8q8), 21.11 (chinzvimbo 17q17), uye 12 (chinzvimbo 18q18) kuwedzera kenza yepancreatic njodzi. Kuvapo kwekopi yega yega mumagenome aya kunowedzera njodzi yekenza yepancreatic ne21.32-15%.
Padanho remumwe nemumwe, pane shanduko isingatauri zvachose cancer, nekuti ivo vanongobatanidzwa neshanduko ine mwero, asi kana zvabatanidzwa, zvinobatsira kunyatsonzwisisa pathogenesis yekenza yepancreatic. Vatsvagiri vacharamba vachiongorora hunhu hwepancreatic cancer, uye kune akawanda majini zvinhu zvatisingazive nezve njodzi yekenza yepancreatic.
Understanding the genetic mutation mechanism of pancreatic cancer can better develop targeted drugs, which will set off a wave of pancreatic cancer treatment. There are many targeted drugs on the market for other cancers. For different types of mutant genes, targeted drugs are used to reduce side effects and improve efficacy. Therefore, it is recommended that cancer patients must pay attention to the benefit space of targeted therapy and conduct genetic testing before medication.
Makambani makuru ane chiremera anogona kusarudza kuita geneti yekuongorora gomarara ndiAmerican Kerrys, American Foundation, uye epamba anaPansheng, Shihe Gene. Global Oncologist Network inogona kubatsira varwere vane magene ekuyedza panguva yese iyi. Varwere vanogona kubvunza iyo Global Oncologist Network kuti vabvunze.
Referensi: https://medicalxpress.com/news/2018-02-genetic-linked-pancreatic-cancer.html
