Zvakanakira zvekuonekwa nekukasira mukuvhenekwa gomarara hazvigone kurerutswa. Kune humbowo hwakawanda hwekuti kukosha kwekupindira nekukurumidza hakungogone kudzivirira kupararira kwechirwere, asiwo zvakanyanya kuvandudza huwandu hwekupona kweanenge marudzi ese ekenza. Nekudaro, kuziva zviratidzo zvekutanga zvegomarara zvinoramba zvichinetsa kune vesainzi. Kunyangwe iye zvino, vaongorori veBrunel University neLeeds University muLondon vachangobva kuburitsa humbowo hutsva hunogona kupa tariro yekuzivikanwa kwekutanga kwegomarara rechiropa.
Migumisiro yekudzidza inoratidza kuti kutaura kweglycolytic enzymes muropa re-pre-cancer cirrhosis inowedzera zvakanyanya, iyo inobatana nehuwandu hwehuwandu hwekuita hepatocellular carcinoma (HCC), uye inogona kuziva mapoka ari pangozi yeHCC yakaipa. Mhedzisiro yechidzidzo chitsva ichi yakabudiswa mu "Forefront of Cellular and Developmental Biology" ine zita rekuti "Kutaura kwakanyanya kweglycolytic majini muchiropa cirrhosis kunobatanidzwa nenjodzi yekuva nekenza yechiropa."
Mune mamwe mazwi: kutendeuka kweglycolysis kunoitika munguva yeprecancerous, chiyero chekutaura kwemajini ane chokuita neglycolysis anonyatsoenderana nekufambira mberi kwechiropa chechiropa kusvika kuHCC, uye kufungidzira kwevarwere vane biopsy HCC yakaipa. Izvi zvinoratidza kuti kutaura kweglycolytic enzymes kunogona kushandiswa sechitsva chebiomarker kufanotaura njodzi yeHCC kune varwere vane chiropa cirrhosis munguva inotevera. Kumwe kutsvagurudza kunodiwa kuti uone kana shanduko idzi mukutaura kwejeni dzakasimbiswa sekuchinja mukuita kweglycolysis.
Mhedzisiro yechidzidzo ichi inoratidza nzira dzinovimbisa dzekuvandudza kurarama kweHCC kuburikidza nekukasika kuvhenekwa nekurapwa. Maererano naDr. Papa, kuchinja kweglycolysis expression profile mumasero e-cirrhotic angatove chinangwa chemishonga mitsva yeHCC. Semuenzaniso, miedzo yekiriniki ikozvino iri kuenderera mberi kuongorora basa rema statins-anoshandiswa kubatsira kudzivirira chirwere chemwoyo, HCC kukura kune varwere vane chiropa chechiropa kana kudzoka kweHCC mushure mekuvhiyiwa kubviswa, zvichida nekuvhara cholesterol synthesis, statins inhibit Glycolysis.
