Ruiwen Zhang naRobert L. Boblitt vanobva kuYunivhesiti yeHouston vakagadzira mushonga mutsva wepancreatic cancer. Tsvakurudzo yakabudiswa mu Journal of Cancer Research. Mushonga uyu unotarisa majini maviri panguva imwe chete, uye kubudirira uku kwakakosha zvikuru pakurapa kwehasha nekuuraya. pancreatic cancer.
Mushonga uyu unotarisirwawo kuve hwaro hwekuvandudza mishonga yekurapa mamwe marudzi ekenza kana zvimwe zvirwere. Kenza yepancreatic inoitika apo maseru epancreatic anotanga kuwanda kubva mukudzora uye kukura kuita mapundu, uye maseru egomarara anokonzerwa anogona kupinda mune dzimwe nhengo dzemuviri. Makenza mazhinji anotangira munzvimbo yepancreas inogadzira enzyme yekugaya. Zviratidzo zvinosanganisira kurwadziwa shure kana mudumbu, kurasikirwa uremu kusingatarisirwi, uye jaundice (yero ganda). Mukuwedzera, weti yemunhu inogona kuoneka yakasviba yero uye ganda rinokwenya. Kune maviri oncogenes ane hukama nepancreatic cancer. Pane nzira mbiri huru dzekuti mushonga uvhare pancreatic cancer. Vanoshandisa nuclear yenyu yeT cell 1 (NFAT1) uye murine double microparticle 2 (MDM2), zvichiteerana. Jeni rekupedzisira rinoronga a tumarara suppressor gene inonzi p53. Kana pasina bundu suppressor p53, MDM2 inogona kukonzera cancer. NFAT1 inoshandiswa kusimudza-kutonga kutaura kweMDM2, nekudaro ichikurudzira kukura kwebundu. Zvinhu zvine chekuita nekudya, kudya uye zvakatipoteredza zvinogona kutungamirira kukuwedzera kwemazinga eizvi zvinhu muchitokisi.
Kana vachitaura nezvekuwanikwa uku, Dr. Zhang vakati izvo zvipatara zvinodiwa zvemishonga mitsva, inoshanda uye yakachengeteka yekurapa kenza yepancreatic haisati yasangana. Zvatinowana zvinomiririra kufambira mberi kukuru mukutsvaga kwekenza. Iye akawedzera, kuti: “Mishonga mizhinji inonangidzira bedzi chinhu chimwe. Isu takatarisa mukomboni inotarisa magene maviri ane chekuita nekenza. “Mushonga mutsva chinhu chakagadzirwa cheMA242. Mushonga unogona kutora mapuroteni maviri panguva imwe chete, nokudaro ichivandudza huturu kuuraya kushanda.
