Pancreatic cancer parizvino ndeimwe yeakanyanya kuuraya uye chemotherapy-resistant cancers. Munguva pfupi yapfuura, vaongorori vegomarara muAustralia vakagadzira nzira inovimbisa nanomedical inovandudza kurapwa kwegomarara repancreatic.
This technology wraps drugs that can silence specific genes in nanoparticles and transport them to pancreatic tumors . It is expected to provide pancreatic cancer patients with alternatives to traditional treatments such as chemotherapy.
Experiments conducted on mice showed that the new nanomedicine method reduced tumarara growth by 50% and also slowed the spread of pancreatic cancer.
Tsvagiridzo yakaburitswa muBiomacromolecule yakaitwa nemasayendisiti kubva kuYunivhesiti yeNew South Wales (UNSW). Inounza tariro nyowani kune vazhinji vanorwara nekenza yepancreatic vanogona kungorarama kwemwedzi mitatu kusvika kumatanhatu mushure mekuongororwa.
Dr. Phoebe Phillips kubva kuUNSW Roy Cancer Research Center (Lowy Cancer Research Center) ndiye akanga ari munhu mukuru wekudzidza. Akataura kuti pese pavaifanira kuzivisa varwere vekenza yepancreatic, Kunyangwe iwo akanakisa chemotherapy mishonga inogona kungovabatsira kuwedzera hupenyu hwavo kwemavhiki gumi nematanhatu, vanachiremba havatsungiririke.
Dr. Phillips akati: “Chikonzero chikuru nei chemotherapy isingashande ndechokuti mapundu epancreatic ane mavanga akawanda, ayo anogona kuita 90% yebundu racho rose. Scar tissue inoita sechivhariso chemuviri chinodzivirira zvinodhaka kusvika pabundu, zvichikonzera gomarara repancreatic. Masero anopokana nechemotherapy. “
She explained: “Recently, we have discovered a key gene that promotes the growth, spread and resistance of pancreatic cancer-βIII-tubulin. Inhibiting this gene in mice not only reduced tumor growth by half, It also slows down the spread of cancer cells. “
Nekudaro, kudzvanyirira jena iri pakiriniki, munhu anofanirwa kukunda kuoma kwekutonga kwezvinodhaka: kuyambuka mavanga epancreatic tumors. Kugadzirisa dambudziko iri, vaongorori vekuAustralia vakagadzira nano-mushonga nzira, iyo diki mamorekuru eRNA (anogona kunzwisiswa sekopi yemasero eDNA) akaputirwa mumhando yepamusoro nano-particles, aya mamorekuru eRNA anosvika bundu mushure mekunge akwanisa yakakura, inhibisa iyo βIII-tubulin gene.
Vatsvagiri ava vakaratidza kugona kweiyo nanoparticles mumakonzo. Nanoparticles yavo inogona kuendesa mishonga yekurapa yemicroRNA kune pancreatic tumors mumakonzo pamberi pevanga renyama, uye nekubudirira kurambidza βIII-tubulin.
"Zvakakosha tekinoroji yedu yenanomedicine ndeyekuti inotarisirwa kudzvanya gene ripi rinosimudzira bundu, kana seti yemajini 'akagadzirirwa pachivande' zvichibva pakutaura kwegene remurwere." Dr. Phillips vakadaro.
"Kubudirira uku kuchabatsira vanhu kuti vagadzire marapirwo matsva ekenza iyi isingarapike nemushonga uye nekuvandudza kushanda kwenzira dziripo dzemakemotherapy, zvichidaro kuvandudza kupona uye hupenyu hwevarwere vepancreatic cancer."
