Mingyang Rwiyo rweHarvard Medical School uye Massachusetts General Hospital yakashuma kuti mushure mekuongororwa kwe-non-metastatic colorectal cancer, kunwa yakawanda fiber kunoderedza kufa chaiko uye kufa kwese kwegomarara reruvara. Kuwedzera fiber kudya mushure mekuongororwa kunogona kubatsira varwere vane kenza yakajeka. (JAMA Oncol. Vhezheni yepamhepo muna Mbudzi 2, 2017).
Although it has been shown that high dietary fiber intake reduces the risk of colorectal cancer, it is not clear whether high fiber intake will benefit colorectal vakapona gomarara.
Kuti uongorore hukama pakati pefibre kudya uye kufa, chidzidzo ichi chaisanganisira varwere ve1575 vane danho I kusvika III kenza yakajeka kubva kune vaviri vangangoita macohort; mushure mekugadzirisa zvimwe zvingangodaro zvekupona zvegomarara, iyo yakajeka kenza yakatarwa yakatemwa Kufa uye kufa kwevakafa.
Pakati pemwedzi mitanhatu nemakore mana mushure mekuongororwa kwekenza yakajeka, vaongorori vakashandisa bvunzo remibvunzo rakagadziriswa pahuwandu hwekudya kuongorora huwandu hwefibre inotora, huwandu hwefibisi kubva kunzvimbo dzakasiyana uye huwandu hwegorosi rose.
Among the 1575 participants, 963 (61.1%) were women; the average age was 68.6 years. With a median follow-up of 8 years, 773 patients died, of which 174 died from colorectal cancer. A high total fiber intake after diagnosis is associated with a lower mortality rate. For every 5g increase in daily intake, the multivariable HR for colorectal cancer specific mortality and all-cause mortality were 0.78 (95% CI 0.65 ~ 0.93; P = 0.006) and 0.86 (95% CI 0.79 ~ 0.93) P <0 .001). According to fiber sources, cereal fiber can reduce colorectal cancer-specific mortality (for every 5 g / d increase in intake, HR = 0.67, 95% CI 0.50 ~ 0.90; P = 0.007) and all-cause mortality (HR = 0.78, 95% CI 0.68 ~ 0.90; P <0.001); vegetable fiber can reduce all-cause mortality (HR = 0.83, 95% CI 0.72 ~ 0.96; P = 0.009), but it does not reduce colorectal cancer-specific mortality (HR = 0.82, 95% CI 0.60 ~ 1.13; P = 0.22); No correlation was found between fruit fiber and mortality. Ingestion of whole wheat food can reduce the specific mortality of colorectal cancer (for every 20 g / d increase in intake, HR = 0.72, 95% CI 0.59 ~ 0.88; P = 0.002), but the correlation It will weaken after entry (HR = 0.77, 95% CI 0.62 ~ 0.96; P = 0.02).
