Colorectal cancer
Vatsvakurudzi vakawana kuti kuwedzera SIRT kune chemotherapy kunogona kuvandudza mwero wekupona we kenza yakajeka
Tsvagiridzo nyowani inoratidza kuti kune varwere vane colorectal cancer vanongove nechiropa metastases kana kunyanya metastases echiropa, kuwedzera kusarudzwa mu vivo radiotherapy zvichienderana neyakajairwa yekutanga-mutsara mFOLFOX6 chemotherapy inogona kuwedzera zvakanyanya yepakati nguva yekupona kwevarwere vane mazamu ekutanga kurudyi.
Muzvinafundo Guy van Hazel weYunivhesiti yeWestern Australia akati: “Zvatinowana zvinoda kumwe kusimbiswa, saka tinogona kufunga nezvemashandisirwo ekutanga kune varwere vane mamota ekutanga echiropa ane metastatic colon cancer (mCRC) anongova nematastases echiropa kana kunyanya chiropa metastases. Zvepabonde muvivo radiotherapy (SIRT). "Akawedzera:" Izvi zvakawanikwa inhau dzakanaka kune varwere vane mamota ekurudyi. Vane fungidziro yakashata uye mashoma ekurapa sarudzo pane varwere vane mamota kuruboshwe. “
Iyo nzvimbo yemCRC yepakutanga bundu yakakosha yekufungidzira chinhu uye fungidziro yemhinduro yekurapa. Semuenzaniso, ongororo ya2016 yakaratidza kuti varwere vane mapundu ekutanga kurudyi vaive nehurombo kupindura uye kufungidzira pane varwere vane matomu ekutanga kuruboshwe.
Kuedza kushanda pamwe nekuchengeteka kweSIRT
SIRT chimiro chemu vivo radiotherapy yeY-90 resin microspheres, iyo inoitiswa kuburikidza neye intrahepatic arteri catheter. Beta radiation microspheres inosarudza kusvika kune microvascular system yakatenderedza bundu, iyo inogona kudzora systemic mhedzisiro.
Iyo SIRFLOX, FOXFIRE uye FOXFIRE zvidzidzo zvepasirese zvakashandiswa kuongorora kushanda pamwe nekuchengeteka kwetambo yekutanga oxaliplatin-based chemotherapy pamwe neSIRT yemhedzisiro isingagadzirisike mCRC. Muongororo yakabatanidzwa, varwere makumi mashanu nevashanu vakagamuchira chemotherapy pamwe neSIRT, uye varwere makumi mashanu nevapfumbamwe vakagamuchira chemotherapy chete. Iyo yepakati medhi yekupona nguva yaive 554 uye 549 mwedzi, zvichiteerana. Mukuongorora kwekupedzisira-kufa, iko kwaive nebundu rekutanga kwaiwanikwa zvine mutsindo paboka remushumo wenyaya. Bundu chairo rakatsanangurwa seimwe bundu rekutanga pamagumo ekupedzisira eiyo splenic kushanduka, uye bundu rekuruboshwe rakatsanangurwa sechero bundu pane iyo splenic flexure, kure kure nekoloni kana Primary bundu mune rectum.
SIRT pamwe chemotherapy inogona kuwedzera nguva yekupona
Mhedzisiro yacho yakaratidza kuti yepakati nepakati nguva yekurarama kwevarwere vane mCRC yakasiya tumarara yaive mwedzi makumi maviri nemana makumi matanhatu nematanhatu mukemotherapy pamwe neboka reSIRT, nemwedzi 24.6 mune chemotherapy boka roga. Nekudaro, yepakati nepakati nguva yekupona yeMCRC chaiyo tumota varwere yaive mwedzi makumi maviri nemaviri mukemotherapy pamwe neboka reSIRT, nemwedzi 26.6 mune chemotherapy boka roga. Chiyero chakajairika chekuyedza kwekurapa nguva yekurarama kwese nenzvimbo zvinoratidzawo kuti bundu reronda rakanyanya kukosha.
Imwe fungidziro ndeyekuti mabundu ekurudyi haangove ane fungidziro yehurombo, anonyanya kurwisa chemotherapy, uye anogona kuve akanyanya kutarisisa kurapwa nemwaranzi ine nzira yakasiyana zvachose yekuita.
Iko kushomeka kwemhedzisiro mhedzisiro mukuwongorora kwese kunogona kuve kuri nekuda kwekuisirwa kwevarwere vane extrahepatic tumor metastases. Kunyangwe SIRT ichikwanisa kudzora kusagadzikana kwechiropa, haigone kudzora kusagadzikana kwe extrahepatic.
