Masayendisiti paTrinity College Dublin (TCD) vakagadzira mushonga mutsva unogona kubatsira kurapa isingawanzo nyoro nyoro sarcoma inobata vechidiki. Synovial sarcoma igomarara rakaoma kurapa nekuda kwekushanduka kwemajini. Inonyanya kuwanikwa mumakumbo kana maoko, uye inogonawo kuonekwa chero kupi zvako pamuviri.
Kune varwere vane bundu size 5-10 cm, iyo yekupona mwero mushure memakore gumi iri pasi pechetatu. Iyo TCD timu yakashandisa CRISPR gene yekuongorora tekinoroji kuti ione zvingangodaro zvekurapa zvinangwa mune zvecancer biology. Vakawana puroteni inonzi BRD9, inogona kuvimbisa kupona kwemasero e synovial sarcoma nekushanda pamwe neprotini yeSS18-SSX inokonzera kukura kwezvirwere.
Masayendisiti aya akabva agadzira mushonga unonanga nekudzikisira BRD9 protein. Mukuyedza vachishandisa mbeva, vakaona kuti mishonga yavakagadzira inogona kudzikisira BRD9 protein nekuibvisa kubva kumasero ekenza, ayo aigona kubudirira kudzivirira bundu kukura. Munyori anotungamira wedzidzo, Dr. Gerard Brien, akati, "Izvi zvinoita kuti masero abvise mapuroteni avanovimba nawo, zvoita kuti vafe." Chikwata chakaona zvakare kuti mushonga uyu haukanganise maseru enzira yemasero akajairwa, izvo zvinokonzeresa mashoma maSide madhara (kana paine mhedzisiro). Vatsvagiri 'chirongwa chinotevera chichava chekuyedza mushonga mutsva uyu muvarwere' miedzo yekiriniki, uye masayendisiti anotarisira kuti mishonga iyi ichapinda mukiriniki munguva pfupi iri kutevera. Tsvagiridzo iyi yakaburitswa mupepanhau repasi rese "eLIFE".
