Os tumores neuroendócrinos pancreáticos (TNEs) geralmente crescem lentamente e o laboratório monitora o tumor em busca de sinais de crescimento por meio de exames de imagem. Pacientes com TNE se espalhando pelo pâncreas geralmente apresentam sintomas como diarreia ou problemas hormonais. Eles podem ser usados para medicamentos como octreotide, lanreotide, diazoxide e inibidores da bomba de prótons, que podem inibir o crescimento do tumor.
When the patient’s symptoms cannot be controlled or the scan shows signs of tumor growth, further treatment is required, and chemotherapy or targeted drugs (such as sunitinib or everolimus) can be used. For people with poorly differentiated tumors (neuroendocrine carcinoma), chemotherapy is the first choice. For patients who have spread to the liver, choose surgery or ablation technology for treatment according to their own conditions. For adults with somatostatin (a hormone) receptor-positive pancreatic neuroendocrine tumor, the radiopharmaceutical Lutathera (l Lu177 dotatate) is a treatment option.
If all feasible treatments no longer work, then consider participating in clinical trials to test new therapies. Participation in clinical trials is likely to benefit some patients.