Британийн эрдэмтэд хүүхдийн хавдрын генетикийн шинжилгээ хийж эхэлжээ. Их Британийн эрдэмтэд генетикийн шинжилгээ нь залуу өвчтөнүүдэд илүү шинэ, илүү хувийн эмчилгээ хийх боломжийг олгож, тэдний амьд үлдэх хугацааг нэмэгдүүлнэ гэж найдаж байна. Шинэ сорил нь хорт хавдрын 81 төрлийн генийн өөрчлөлтийг шинжилдэг.
Scientists say the test will lead to “a higher level of playing field” and accelerate children’s access to important new drug treatments. The test was performed at the Royal Marsden National Health System Hospital in London and will be tested on 400 children from all over the UK over the next two years.
The test has been implemented with genetic funding from the National Institutes of Health (NIHR) foundation and the Хавдар Institute. A charity called Christopher has provided more than £ 300,000 in funding to develop the test. The organization was founded by a couple whose children died of invasive тархины хавдар at the age of six.
This is a real first step towards personalized хорт хавдрын эмчилгээ for children,” said Christopher’s parents, Karen and Kevin Capel. Christopher got a generic хавдар. Hopefully, in the future, children will know exactly what type of tumor they have.” “We almost feel that the treatment for the child is not to kill the cancer, but to kill our child.”
“He used to be a healthy, happy, very athletic 4-year-old kid. But he became unable to speak or even eat on his own, and lost weight. “In the year he was diagnosed, he was unable to grow into a child of his age. We tried to keep him from other children.”
Хорт хавдар нь хүүхдүүдэд маш ховор тохиолддог, өвчтөний популяци олон байдаггүй, мөн Эмнэл зүйн туршилт for pharmaceutical companies will lack motivation. This means that children will miss the opportunity to receive targeted treatments for cancer cells without damaging healthy cells with innovative therapies.
Professor Louis Chesler, who is leading the genetic testing research, said: “Children often don’t have equal access to the most advanced and potentially beneficial cancer treatments.” “The cost of developing gene-targeted drugs is very high. They tend to Test it on adults first so that more people can get treatment and the results can be seen faster. ”
"Энэ шинжилгээ нь хавдрын бүх генетикийн өөрчлөлтийг маш тодорхой тодорхойлох тул гайхалтай ахиц дэвшил юм." “Генийн шинжилгээ нь эмч нарт хүүхдэдээ тохирсон эмийг сонгох, чадах бүхнээ хийхэд нь туслах маш хүчирхэг хэрэгсэл болж өгдөг. Эдгээр эмийн үр нөлөөг хурдан тодорхойлох боломжтой байж магадгүй юм. ”
Children’s tumors are usually genetically simpler than adult tumors, so eventually these drugs may be more effective in children.” The goal of генетикийн шинжилгээ is to give scientists and doctors detailed genes for childhood tumors within a few weeks of diagnosis. information.
Genetic testing gives doctors strong evidence to use зорилтот эмчилгээ for younger patients, potentially preventing these patients from experiencing the side effects associated with traditional chemotherapy and radiation therapy.
Jack Daly, 14, from Wokingham, was diagnosed with a brain tumor when he was 7 and is now a brain tumor амьд үлдсэн. Radiotherapy helped save his life, but left him with sequelae. “My athletic ability is not very good,” Jack said. “I have to get someone to help me dress and undress at school.” “My balance is not good-I am awkward and often fall. I worked hard at school, where I found friendship.” Jack and his mother, Helen, use their donations to make ends meet in Capels-hoping that генетикийн шинжилгээ will make a huge difference in the quality of life of future children.
“Жек хорт хавдраасаа ангижирсан тул хүмүүс энэ асуудлыг үнэндээ олж харахгүй байна. Түүнд тэргэнцэр дээр суух шаардлагагүй. Түүнд боолт зүүх шаардлагагүй ”гэж Хелен хэлэв.
“Хэрэв та Жакийг харж байсан бол тэр ердийн өсвөр насны хүүхэд шиг харагдаж байна. Гэхдээ таны олж харахгүй байгаа зүйл бол эмчилгээний улмаас тархины эдэд гэмтэл учруулах явдал юм. ”
Энэ нийтлэлийн эх сурвалж URL: http://www.bbc.com/news/health-35918744
