A me et systematicam review Sakuraba et alia tradit de Clarendonta analysi proventus ostendunt aegros cum morbo iecoris chronici altiorem periculum canceris colorectalis habere (CRC), etsi hi aegros translationi iecoris recipiunt, hoc periculum adhuc exstat. (Gastrointestinal Endosc. Versio electronica die 21 Decembris 2016)
Sakuraba dicitur quod pro causa iecoris morbo, iecoris morbo in patientibus longos altiorem periculo CRC, et periculum existit etiam iecur post translationi. Ideo patientibus longos iecoris morbo ne et opposita texit potest monitored ad alacrius producendum ad redigendum periculo CRC.
Sakuraba et al. Quanquam in periculo longos iecoris morbo ante et post aegris in CRC iecoris translationi. Inquisitores enim de studiis searched in periculo longos iecoris morbo, et in in electronic CRC database et opposita texit summa studia L LV CMXCI in aegris. Secundum Sakuraba, in studiis, quae aegros hepatitis et cirrhosin includunt, tota rate incidentia normatis (SIR) erat 2.06 (95% CI 1.46 ~ 2.90, P <0.0001), et heterogeneitas moderata (I2 = 49.2%) Haec est. Maxime ob differentias morborum subgroups et inquisitionis intensio.
Tres studiis ostenditur quod cum aegris prima sclerosing cholangitis (PSC), habent augeri periculo CRC (SIR = 6.70, XCV% C 95-3.48: P <12.91) et modicum circa Heterogenei Luminis (I0.0001 = 2%), manifestum est ex quanta sit differentia in ardore ad investigationis. Illa studia, quae includitur in aegris qui subiit transplantatio iecoris et BONE erant 36.3 (XCV% ad 2.16 C. I 95: P <1.59); et modica Heterogenei Luminis (I2.94 = 0.0001%).
In meIn ta analysi, proportio morborum hepatis autoimmune relatarum ad periculum CRC relata est. Sakuraba dixit, “Supra visum est solum PSC aegros CRC periculum augeri, sed investigatio nostra ostendit periculum CRC inter aegros cum aliis morbis longis iecoris etiam augeri. Idem auctarium ipsum. "
Patrick Boland from the Roswell Park Cancer Institute in New York is not a member of the study. He pointed out that most of the patients in the study have cirrhosis, PSC or have received liver transplantation. The risk of CRC in PSC patients is particularly obvious. PSC is associated with inflammatory bowel disease, which is a known risk factor for colonia cancer, which is also the strongest evidence. However, those who have undergone liver transplantation, especially those with underlying autoimmune diseases, have an increased risk of CRC. Organ transplantation requires the use of immunosuppressive agents, which puts the patient at risk of secondary malignancy for a long time. They have evidence that kidney transplant patients have an increased risk of colon cancer. The data from this study showed that the risk of colon cancer in patients who underwent liver transplantation would be doubled.
Boland inventa sunt haec nova quia in periculo factores inflammationem Virus colonia cancer. Qui credit quod sit colonoscopy partem iecoris metastases de manu examen, praesertim cum aegris PSC. Necnon et hoc quod similitudines anorum contingat in diversis partibus, quae biologicae differences grandi magna intestinum, erit adhuc est interesting morbo periculo an studio maxime ad dextram sive ad sinistram colonia.
