Saboda rarrabuwar cutar sankarar jini da rarrabewar hangen nesa suna da rikitarwa, babu wata hanyar da ta dace-da-dukkan hanyar magani, kuma ya zama dole a haɗa ƙididdigar hankali da ƙaddamar da hangen nesa don tsara tsare-tsaren magani. At present, there are mainly the following types of treatment methods: chemotherapy, radiotherapy, targeted therapy, immunotherapy, stem cell transplantation, etc.
Ta hanyar ingantaccen magani, an riga an inganta hangen nesa na cutar sankarar bargo. Mafi yawan marasa lafiya na iya warkewa ko kwanciyar hankali na dogon lokaci. Zamanin cutar sankarar bargo a matsayin "cuta mara warkarwa" ya wuce.
AML magani (ba M3)
Yawanci ya zama dole a fara aiwatar da hade-hade, abin da ake kira "shigar da cutar sankarawa", yawanci ana amfani da makircin DA (3 + 7). Bayan farfaɗar shigarwa, idan an sami gafartawa, za a ci gaba da ingantaccen maganin ƙwaƙwalwar ƙwayar cuta ko hanyoyin dasa ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayarfancin ƙwayar ƙwayar ƙwayar cuta ta hanyar ƙarancin ƙwallon ƙafa ta hanyar haɓakawa, idan an sami gafara, ci gaba da inganta haɓakar ƙwayar cuta ko ƙwayoyin ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar ƙwayar cuta ta hanyar ƙira da ƙwayoyin cuta da ƙwayoyin cuta. Bayan kulawa ta ƙarfafawa, yawanci ba a yin maganin kulawa a halin yanzu, kuma ana iya tsayar da maganin don kallo kuma a bi su akai-akai.
M3 magani
Due to the success of targeted therapy and induced apoptosis therapy, PML-RARα positive acute promyelocytic leukemia (M3) has become the best prognostic type in the entire AML. Studiesarin karatu da yawa sun nuna cewa duk-trans retinoic acid haɗe tare da maganin arsenic na iya warkar da mafi yawan marasa lafiya da M3. Maganin yana buƙatar aiwatarwa daidai gwargwadon aikin jiyya, kuma tsawon lokacin kulawa na kulawa a cikin lokaci na gaba shine yawanci ƙaddara ta yanayin saura na ƙwayoyin haɗin.
DUK magani
Uunƙarar ƙwayar cuta yawanci ana yin ta farko, kuma akwai bambance-bambance a cikin makircin da aka saba amfani da shi tsakanin manya da yara. Koyaya, a cikin yan shekarun nan, karatu ya nuna cewa sakamakon amfani da tsarin yara don kula da marassa lafiyar manya na iya zama mafi kyau fiye da tsarin manya na gargajiya. Bayan gafartawa, ya zama dole a dage kan ƙarfafawa da kulawa. Marasa lafiya masu haɗari suna da yanayin yin dashen ƙwayoyin halitta. Marasa lafiya tare da Ph1 chromosome tabbatacce ana ba da shawarar don magani tare da masu hana maganin tyrosine kinase.
Magungunan cutar sankarar jini na yau da kullum
In the chronic phase, tyrosine kinase inhibitors (such as imatinib) are the preferred treatment. It is recommended to treat them as soon as possible and in sufficient amounts. Delayed use and irregular use can easily lead to drug resistance. Therefore, if you decide to use imatinib, first of all, do not delay, and secondly, you must insist on long-term use (close to life), and do not arbitrarily reduce the amount or stop taking it during taking it, otherwise it will easily lead to drug resistance. The accelerated phase and the acute phase usually require targeted therapy (imatinib uptake or the use of second-generation drugs). If possible, allogeneic transplantation or timely combination therapy can be accepted.
Magungunan lymphocyte na kullum
Early asymptomatic patients usually do not need treatment, and in the late stage, they can choose a variety of chemotherapy options, such as Liu Keran monotherapy, fludarabine, cyclophosphamide combined with merova, and other chemotherapy. Bendamustine and anti-CD52 monoclonal antibodies are also effective. In recent years, it has been found that targeted therapy of BCR pathway inhibitors may have a significant effect. Patients with refractory conditions can consider allograft therapy.
Jiyya na cutar sankarar bargo ta tsakiya
Kodayake nau'ikan M4 da M5 a cikin ALL da AML ana haɗuwa da su tare da CNSL, wasu cututtukan sankarar bargo kuma na iya faruwa. Saboda magungunan da aka saba amfani dasu suna da wuyar shiga shingen ƙwaƙwalwar jini, waɗannan marasa lafiya yawanci suna buƙatar huɗa lumbar don hanawa da magance CNSL. Wasu marasa lafiya marasa lafiya na iya buƙatar maganin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar.
Ban da wasu ƙwararrun marasa lafiya na musamman waɗanda za su iya amfanuwa da dasawar kai tsaye (yawan sake fasalin da aka yi wa autologous yana da girma sosai), yawancin masu cutar sankarar bargo ya kamata su zaɓi xenotransplantation don dasawa.
A takaice, babban layin farko na cutar sankarar jini ba dasawa bane. Kodayake dasawa na iya samun ingantacciyar rayuwa, rikitarwa irin su saurin komowa da cututtukan dasa-hannu da rigakafi na iya shafar ingancin rayuwar marasa lafiya. Jiyya bayan sake dawowa zai zama da wuya. Sabili da haka, dasawa gabaɗaya shine zaɓin ƙarshe na ƙarshe.
