Gano kansar mahaifa
Is it safe to extend the screening interval to 5 years or more after a negative screening result? A new study shows that the risk of cervical cancer after one or more combined HPV tests and cytology screening results is negative Is significantly reduced. The study found a follow-up analysis of 1 million female subjects. The analysis showed that the risk of invasive ciwon sankarar mahaifa and cervical CIN3 lesions decreased with each round of combined testing and screening. This risk reduction is most significant between the first and second rounds, and is more significant than the second and third rounds. (Ann Intern Med. November 27, 2017 online version)
Sharuɗɗan gwajin cutar kansar mahaifa suna canzawa, musamman tare da rigakafin HPV. Buga na 2015 na jagororin ACOG ya ba da shawarar cewa za a iya amfani da gwajin HPV azaman madadin hanyar tantancewa ga mata sama da shekaru 25. Ana ba da shawarar karɓar cytology kowane shekaru 3. An kuma nuna cewa an fi so a haɗa cytology da gwajin HPV. Daftarin jagorar USPSTF yana ba da shawarar gwada manyan nau'ikan haɗarin HPV kawai. A matsayin madadin cytology mai sauƙi ga mata fiye da 30, gwajin haɗin gwiwa ba a ba da shawarar ba.
Masu binciken sun nuna cewa babu hujjoji masu yawa game da ingancin gwajin HPV, kuma galibin binciken da aka buga na HPV ya ta'allaka ne akan zagayen binciken. Masu binciken sun binciki mata 990013 wadanda suka yi gwajin hadin gwiwa daga 2003 zuwa 2014, kuma suka binciki canjin da ke tattare da cutar sankarar mahaifa bayan sakamakon gwajin hadin gwiwa a jere ba shi da kyau.
Binciken ya gano cewa yayin da sakamakon mummunan sakamakon gwajin da aka haɗa ya karu, haɗarin ciwon daji na mahaifa da kuma ≥CIN3 raunuka ya ci gaba da raguwa, kuma mummunan tasirin gwajin haɗin gwiwa na farko yana da tasiri mafi girma akan rage hadarin. A cikin kowane zagaye na nunawa, tasirin sakamakon gwajin HPV mai tsabta akan haɗarin ciwon daji yana da daidaito, ba tare da la'akari da sakamakon gwajin cytological ba, ba tare da la'akari da sakamakon gwajin da aka haɗa ba. Wadanda ba su da kyau ga gwajin HPV na farko sun sami raguwar shekaru 5 a cikin haɗarin ciwon daji na mahaifa na 0.0092%, kuma waɗanda ke da mummunan sakamakon gwaji na uku sun sami raguwar 0.0015% a hadarin; Haɗarin shekaru 3 don cutar kansar mahaifa mara kyau ga gwaje-gwaje na farko da na uku Rage da 0.0081% da 0.0015%. An rage mummunan haɗarin cytological na ciwon daji na shekaru uku da 0.0140% da 0.0023%, bi da bi.
Wani mai bincike yayi sharhi cewa binciken ya nuna cewa a gwajin hadin gwiwa na farko, matan da basuda cutar ta HPV kawai suna da hatsarin kamuwa da cutar kansa fiye da wadanda suke da gwaje-gwajen marasa kyau, kuma wadanda suke da mummunan sakamako na HPV a gwajin na biyu suka kara rage hadarin na uku Bayan mummunan abu na biyu, ya ɓace gaba ɗaya. A gano raunin CIN3, fa'idodi na haɗuwa da gwaji akan gwajin HPV ƙanana ne. Gwajin haɗin gwiwa kawai ya ƙara colposcopy mara amfani da biopsy kuma kan magani.
